The Secret to Ultimate Skin Success: Why Adding Ultra Ampoules to Your Needling Treatments Changes Everything
- Mima

- Nov 13
- 4 min read
In 2025, the skincare world has shifted toward intelligent ingredient delivery. Instead of simply applying serums after treatments, clinics are now pairing advanced microneedling or RF microneedling with Ultra fractional laser along with high-grade ampoules designed to reach deeper layers of the skin.
At Prestige Laser & Skin Clinic, we use four powerhouse ampoules that elevate every treatment:
TA – Tranexamic Acid
RS – Resveratrol
VC – Vitamin C
VA – Vitamin A (Retinol)
Each of these Ultra ampoules serves a precise function — brightening, repairing, protecting, and renewing — and when combined with needling, they unlock faster, longer-lasting, and more radiant results.
What Makes Ampoules So Powerful?
Ampoules are ultra-concentrated serums, formulated with the highest levels of active ingredients and designed for targeted results. When infused into freshly treated skin during needling, the micro-channels created by the device allow these potent formulas to penetrate deeper and act more efficiently.
Co09ompared to standard skincare, ampoules work like a booster shot for your complexion — delivering transformative results in hydration, tone, texture, and firmness.
The 4 Ultra Ampoules Explained

Below we break down each of the four Ultra ampoules we use most frequently in our clinic, along with their unique benefits and how they enhance your needling treatments.
1. TA — Tranexamic Acid Ampoule
Brightening | Pigmentation | Even Tone
Tranexamic Acid is one of dermatology’s most advanced ingredients for treating hyperpigmentation and uneven skin tone. It works by blocking the communication between melanocytes (pigment-producing cells) and keratinocytes, effectively reducing the formation of dark spots and preventing new ones from appearing.
Key Benefits:
Fades hyperpigmentation, melasma, and sunspots
Calms redness and inflammation
Improves skin clarity and radiance
Safe for sensitive and post-inflammatory skin types
When combined with needling: the controlled micro-injuries open pathways for Tranexamic Acid to reach the lower layers of the epidermis, where pigment is produced. This amplifies its ability to fade stubborn discoloration and leaves skin visibly brighter and more even.
2. RS — Resveratrol Ampoule
Repair | Antioxidant | Barrier Protection
Resveratrol is a naturally occurring polyphenol found in grapes, berries, and red wine — often called the “longevity molecule.” It protects the skin from oxidative stress and environmental aggressors that accelerate aging.
Key Benefits:
Strengthens the skin’s barrier and improves resilience
Provides deep antioxidant protection
Reduces post-treatment redness and irritation
Promotes smoother, more refined skin texture
When combined with needling: RS ampoule supports the skin’s recovery phase by neutralizing free radicals generated during the healing process. This ensures that new collagen forms in a healthy environment, enhancing elasticity and reducing post-treatment downtime.
3. VC — Vitamin C Ampoule
Radiance | Collagen Boost | Antioxidant Defense
Vitamin C remains the gold standard for achieving a bright, luminous complexion. It stimulates collagen synthesis, protects against UV-induced free radicals, and visibly improves tone and texture.
Key Benefits:
Boosts natural collagen production for firmer skin
Reduces pigmentation and dullness
Neutralizes oxidative damage from pollution and sunlight
Leaves skin glowing and refreshed
When combined with needling: Vitamin C ampoules deliver deeper antioxidant protection right into the dermal layer, supercharging your glow while promoting firmer, smoother skin. It’s a favorite for clients who want to radiate confidence after just one session.
4. VA — Vitamin A (Retinol) Ampoule
Renewal | Texture Refinement | Anti-Aging
Vitamin A, often in the form of retinol or retinaldehyde, is a powerhouse for accelerating cell turnover and stimulating collagen. It’s the most clinically proven ingredient for reducing fine lines, wrinkles, and uneven texture.
Key Benefits:
Encourages cell regeneration for smoother skin
Minimizes pores and refines rough texture
Reduces fine lines and wrinkles over time
Enhances firmness and overall youthfulness
When combined with needling: VA ampoule dives deep into the dermal matrix, accelerating the skin’s renewal cycle while amplifying collagen production. The result is firmer, clearer, and more refined skin — without the typical irritation of topical retinol use.
Why Pairing Ampoules with Needling Delivers Superior Results
Combining LaseMD Ultra with RF microneedling along with these four ampoules provides a multi-dimensional approach to rejuvenation:
1. Enhanced Absorption
Needling creates temporary micro-channels, allowing actives to penetrate 70 % deeper than traditional topical application.
2. Accelerated Healing
Repair and antioxidant ampoules (like RS and TA) calm inflammation, reduce redness, and protect the skin barrier, shortening recovery time.
3. Targeted, Customizable Results
Every client’s skin is different. We tailor ampoule combinations to address specific concerns — brightening, repair, firming, or renewal — maximizing treatment efficiency.
4. Amplified Collagen Stimulation
When collagen-boosting ampoules (VC and VA) are applied during or post-treatment, they reinforce your skin’s regenerative phase, giving you smoother, firmer, longer-lasting results.
5. Synergistic Longevity
Ampoules extend your results between sessions — keeping your skin healthier, stronger, and more radiant for months.
How We Customize the Ultra Program
At Prestige Laser & Skin Clinic, our approach is simple but strategic:
Skin Concern | Primary Ampoule | Supporting Ampoule | Expected Benefit |
Pigmentation / Uneven Tone | TA | VC | Brighter, more even complexion |
Post-Treatment Recovery / Redness | RS | TA | Calmer skin, faster healing |
Anti-Aging / Fine Lines | VA | VC | Firmer, smoother skin |
Dullness / Lack of Glow | VC | RS | Fresh, luminous appearance |
The Science Behind the Synergy
During microneedling or RF microneedling, micro-injuries stimulate collagen and elastin production. This controlled trauma also opens pathways that significantly enhance absorption of topically applied actives.
When we follow with LaserMD Ultra treatment and high-grade ampoules — especially those containing antioxidants, peptides, or brightening agents — the ingredients reach optimal depth, influencing fibroblast activity and skin regeneration at a cellular level.
In short: the treatment remodels your skin structure, while ampoules supercharge the biochemical response.
Microneedling RF microneedling creates the foundation for collagen remodeling — but pairing it with LaseMD Ultra treatments and high-grade ampoules (TA, RS, VC, VA) transforms that foundation into artistry.
Each ampoule plays its role:
TA – Brightens and evens tone
RS – Repairs and protects
VC – Energizes and firms
VA – Renews and refines
Together, they deliver the most balanced, comprehensive rejuvenation program available today.
At Prestige Laser & Skin Clinic, we customize every treatment plan to your goals, skin type, and seasonal needs — ensuring you experience visible, long-lasting, and healthy radiance from the inside out.

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